05-22-2020, 10:28 AM
There's yet another Stanford preprint trying to estimate the infection fatality rate of covid-19. This one is from a couple of people in the biology department, so no connection with the med school. https://www.medrxiv.org/content/10.1101/...1.full.pdf
They come up with an IFR of 1.04% (95% limits 0.77-1.38%) by modelling death rates as a function of testing across countries. Basically, they argue that deaths are reported accurately but numbers of cases depend on testing, so the best estimates of IFR should come from places with the most testing.
It's hard to argue with their logic, though I could imagine some different ways to get at the exact relationship. Even if deaths are underreported in less developed countries, that shouldn't affect their model too much--it's the countries with the most testing that have the most influence on the results.
This looks carefully done, though I'd need to spend a couple of hours looking it over to be more sure.
They come up with an IFR of 1.04% (95% limits 0.77-1.38%) by modelling death rates as a function of testing across countries. Basically, they argue that deaths are reported accurately but numbers of cases depend on testing, so the best estimates of IFR should come from places with the most testing.
It's hard to argue with their logic, though I could imagine some different ways to get at the exact relationship. Even if deaths are underreported in less developed countries, that shouldn't affect their model too much--it's the countries with the most testing that have the most influence on the results.
This looks carefully done, though I'd need to spend a couple of hours looking it over to be more sure.
