[DocSavage87]

What do people think? It’s so aggressive yet their situation is so dire. It could in a way be helpful for other countries because they are basically running a massive experiment on their population. I guess this is one way to find out if transverse myelitis is a risk with this vaccine.

It seems a inconsistemt though that the Russian and Chinese rushed, unpublished vaccinations were characterized as dangerous and unethical yet this move is “bold.”

I though Oxford wouldn’t even report until late January to early Feb and  would be approved in early Feb at the earliest. Have they even published Phase 3 preliminary data?

https://www.nytimes.com/2020/12/30/world...eneca.html

LONDON — Britain became the first country on Wednesday to give emergency authorization to the coronavirus vaccine developed by AstraZeneca and the University of Oxford, opening a path for a cheap and easy-to-store shot that much of the world will rely on to help end the pandemic.

In a bold decision to accelerate vaccinations, a British government advisory body directed clinicians to give as many people as possible their first dose of a coronavirus vaccine, without reserving supplies for planned second doses. 

Instead of administering the two shots within a month, clinicians will wait as long as 12 weeks to give people their second doses, the government said, a decision that applies to the Oxford-AstraZeneca vaccine as well as the Pfizer-BioNTech shot that Britain authorized early this month

Hard to say what's going on without studying all the details of the available studies.  Probably their reasoning: (1) there's a fair amount of effectiveness even with one dose from prelim data, (2) even if it doesn't prevent infection, the other main thing you want to reduce is the severe cases that could lead to death, and it seems it's very effective in doing that.

[tweet]
https://twitter.com/trishgreenhalgh/stat...93728?s=20
[/tweet]

[DocSavage87]

What do people think? It’s so aggressive yet their situation is so dire. It could in a way be helpful for other countries because they are basically running a massive experiment on their population. I guess this is one way to find out if transverse myelitis is a risk with this vaccine.

It seems a inconsistemt though that the Russian and Chinese rushed, unpublished vaccinations were characterized as dangerous and unethical yet this move is “bold.”

I though Oxford wouldn’t even report until late January to early Feb and  would be approved in early Feb at the earliest. Have they even published Phase 3 preliminary data?

https://www.nytimes.com/2020/12/30/world...eneca.html

LONDON — Britain became the first country on Wednesday to give emergency authorization to the coronavirus vaccine developed by AstraZeneca and the University of Oxford, opening a path for a cheap and easy-to-store shot that much of the world will rely on to help end the pandemic.

In a bold decision to accelerate vaccinations, a British government advisory body directed clinicians to give as many people as possible their first dose of a coronavirus vaccine, without reserving supplies for planned second doses. 

Instead of administering the two shots within a month, clinicians will wait as long as 12 weeks to give people their second doses, the government said, a decision that applies to the Oxford-AstraZeneca vaccine as well as the Pfizer-BioNTech shot that Britain authorized early this month

Hard to say what's going on without studying all the details of the available studies.  Probably their reasoning: (1) there's a fair amount of effectiveness even with one dose from prelim data, (2) even if it doesn't prevent infection, the other main thing you want to reduce is the severe cases that could lead to death, and it seems it's very effective in doing that.

[tweet]
https://twitter.com/trishgreenhalgh/stat...93728?s=20
[/tweet]