[BostonCard]

The hand-waiving argument I've seen for the half dose is that the full dose produces a vigorous response against the viral vector (the chimpanzee adenovirus) so that when the booster is injected, it is destroyed before it can ever enter cells and thus the spike proteins are never expressed and don't produce an immune response.

BC

[BostonCard]

The hand-waiving argument I've seen for the half dose is that the full dose produces a vigorous response against the viral vector (the chimpanzee adenovirus) so that when the booster is injected, it is destroyed before it can ever enter cells and thus the spike proteins are never expressed and don't produce an immune response.

BC