[BostonCard]

While the possibility of requiring -80 has always been there, we had no idea which vaccine(s) were going to be safe and effective and thus available and when.  There was a universe where there was a delay in the Pfizer/BioNTech data and Oxford/AZ came in first.  Or, you could imagine circumstances where the first three vaccines came in with subpar efficacy, but that the J&J vaccine, which requires only one dose, works better.  We still don't really know the full spectrum of protection in older adults; your distribution plans have to change if only one of the vaccines is effective in older populations.

There are many more moving pieces than you appreciate because the vaccines are not interchangeable and you have to balance efficacy, convenience, storage requirements, etc.

BC

[BostonCard]

While the possibility of requiring -80 has always been there, we had no idea which vaccine(s) were going to be safe and effective and thus available and when.  There was a universe where there was a delay in the Pfizer/BioNTech data and Oxford/AZ came in first.  Or, you could imagine circumstances where the first three vaccines came in with subpar efficacy, but that the J&J vaccine, which requires only one dose, works better.  We still don't really know the full spectrum of protection in older adults; your distribution plans have to change if only one of the vaccines is effective in older populations.

There are many more moving pieces than you appreciate because the vaccines are not interchangeable and you have to balance efficacy, convenience, storage requirements, etc.

BC