[BostonCard]

Another negative observational trial of hydroxychloroquine and COVID-19.

https://jamanetwork.com/journals/jama/fu...ort=MRNRD0

Like the other observational study, this one is hampered by the fact that the patients who received HCQ were sicker, and there is only so much you can do with adjustment.  Again, though, if it were a "game changer" we probably would have seen something.

This will only be settled once the results of the large randomized, placebo-controlled studies come out.  However, at this point, I would be a little surprised if they showed a benefit (though there are plenty of cases where observational studies and randomized, placebo-controlled studies, yielded different results).

BC

[BostonCard]

Another negative observational trial of hydroxychloroquine and COVID-19.

https://jamanetwork.com/journals/jama/fu...ort=MRNRD0

Like the other observational study, this one is hampered by the fact that the patients who received HCQ were sicker, and there is only so much you can do with adjustment.  Again, though, if it were a "game changer" we probably would have seen something.

This will only be settled once the results of the large randomized, placebo-controlled studies come out.  However, at this point, I would be a little surprised if they showed a benefit (though there are plenty of cases where observational studies and randomized, placebo-controlled studies, yielded different results).

BC