Fauci on vaccine development - Printable Version
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Fauci on vaccine development - akiddoc - 03-26-2020
https://www.youtube.com/watch?v=ZrWAqpPGAxQ
By the way, he tangentially touches on the fact that this virus will be around for a while, if not forever. It's likely to turn into a seasonal virus. We need a large percentage of the population to be immune in order for it to not be an every year plague. As was pointed out by Boston Card, the other common Coronaviruses do not impart long-lasting immunity to humans. We'll see what type of vaccines are developed and what type of immunity they provide.
RE: Fauci on vaccine development - 2006alum - 03-26-2020
Thank you for sharing this. Refreshingly zero-BS. Just like the best of New Yorkers. And remarkably on top of everything for someone about to round into his eighth decade on earth.
RE: Fauci on vaccine development - akiddoc - 03-26-2020
(03-26-2020, 08:34 PM)2006alum Wrote: Thank you for sharing this. Refreshingly zero-BS. Just like the best of New Yorkers. And remarkably on top of everything for someone about to round into his eighth decade on earth.Fauci has always been smart. A bit of a politician as well.
A prescient article from 2017:
https://www.healio.com/infectious-disease/emerging-diseases/news/online/%7B85a3f9c0-ed0a-4be8-9ca2-8854b2be7d13%7D/fauci-no-doubt-trump-will-face-surprise-infectious-disease-outbreak
RE: Fauci on vaccine development - OutsiderFan - 03-27-2020
I'm no virologist or anything of the sort, but this thread supports what akiddoc said above:
This virus already has a history of mutating, which makes developing a vaccine challenging. We have flu vaccines but it's not like they are full-proof, as they have been for measles, polio, etc.
[tweet]https://twitter.com/trvrb/status/1242628564324761606[/tweet]
RE: Fauci on vaccine development - BostonCard - 03-27-2020
All viruses mutate; RNA viruses (of which SARS-CoV2 is one example) mutate faster than DNA viruses. It seems like the mutation rate of SARS-CoV2 is lower than influenza. The fact that it mutates doesn't necessarily point to loss of immunity. Loss of immunity to other coronaviruses happens because antibody titers against the virus drop to levels where they no longer provide protection, not because the antigen to which you have antibodies has since mutated.
I will say what I've said before. This is a new virus and we don't have all the data. We should not draw overly definitive conclusions based on what we know about similar viruses and the limited information we have to date. It's ok to speculate, but don't jump to conclusions.
BC
TreesAndBirds - TreesAndBirds - 03-27-2020
From my Stanford connected doctor. He of course did not mean this as definitive. Just as the state of our current knowledge....
“Molecular studies of Coronavirus indicate that the virus does not substantially mutate (in
contrast to the flu, which mutates rapidly). Therefore, a one time vaccine for Coronavirus may be
sufficient to last for multiple years, and a yearly vaccine (like the flu) will probably not be necessary.”
His reference to Coronavirus refers to the current one.
RE: TreesAndBirds - akiddoc - 03-28-2020
(03-27-2020, 08:31 PM)TreesAndBirds Wrote: From my Stanford connected doctor. He of course did not mean this as definitive. Just as the state of our current knowledge....No way for him or her to know that yet. Is he or she an immunologist or an infectious disease physician who does research at Stanford? Stanford "connected" doesn't mean much. My Stanford connected doctor seems to know less than I do. We don't know if an effective and safe immunization will be easy to produce, difficult to produce, or impossible to produce. We don't know how long it will be effective if it is developed. This virus has been mutating slowly, but what really matters is how much change occurs in the portion(s) of the virus you decide to target with your vaccine. Vaccine development is fraught with pitfalls.
“Molecular studies of Coronavirus indicate that the virus does not substantially mutate (in
contrast to the flu, which mutates rapidly). Therefore, a one time vaccine for Coronavirus may be
sufficient to last for multiple years, and a yearly vaccine (like the flu) will probably not be necessary.”
His reference to Coronavirus refers to the current one.
https://academic.oup.com/jid/article/212/suppl_1/S12/1051650